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Home cDNA Clone TrueORF All PLA2G3 ORF Clones

PLA2G3 (NM_015715) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG206872 PLA2G3 (GFP-tagged) - Human phospholipase A2, group III (PLA2G3), 10µg
$590
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for PLA2G3 (NM_015715)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody
TrueORF Data for RG206872
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1530 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Secreted ProteinDruggable Genome
Protein Pathways: Glycerophospholipid metabolismEther lipid metabolismArachidonic acid metabolismLinoleic acid metabolismalpha-Linolenic acid metabolismMetabolic pathwaysMore Pathways >>

Reference Data
RefSeq: NM_015715.2, NP_056530
RefSeq Size: 2593 RefSeq ORF: 1530
Synonyms : GIII-SPLA2; sPLA2-III; SPLA2III
LocusID: 50487 Cytogenetic: 22q12.2
Summary: This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. [provided by RefSeq, Apr 2014].

 

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