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Home cDNA Clone TrueORF All CD74 ORF Clones

CD74 (NM_001025158) Human cDNA ORF Clone

Western Blot Validated

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG206830 CD74 (GFP-tagged) - Human CD74 molecule, major histocompatibility complex, class II invariant chain (CD74), transcript variant 3, 10µg   
$430
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
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0 2 weeks
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TrueORF Data for RG206830
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 483 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: TransmembraneDruggable Genome
Protein Pathways: Antigen processing and presentation

Reference Data
RefSeq Explanation: NM_001025158.1, NP_001020329 RefSeq Size: 1155 RefSeq ORF: 483
Synonyms : DHLAG; HLADG; Ia-GAMMA; II
LocusID: 972 Cytogenetic: 5q33.1
Gene Summary: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF. [UniProtKB/Swiss-Prot Function]

 

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