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Home cDNA Clone TrueORF All P2RY12 ORF Clones

P2RY12 (NM_022788) Human cDNA ORF Clone

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Cat. No. Description Price Availability  
RG205005 P2RY12 (GFP-tagged) - Human purinergic receptor P2Y, G-protein coupled, 12 (P2RY12), transcript variant 1, 10µg
590
3-4 weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for P2RY12 (NM_022788)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RG205005
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1029 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: GPCRTransmembraneDruggable Genome

Reference Data
RefSeq: NM_022788.3, NP_073625
RefSeq Size: 1502 RefSeq ORF: 1029
Synonyms : ADPG-R; BDPLT8; HORK3; P2T(AC); P2Y(12)R; P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12; SP1999
LocusID: 64805 Cytogenetic: 3q24-q25 Domains: 7tm_1
Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013].

 

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