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 Home cDNA Clone TrueORF All EDNRB ORF Clones

EDNRB (NM_000115) Human cDNA ORF Clone

Western Blot Validated

Specifications Citations (1) Clone of Other Species Product Documents
Cat. No. Description Price Availability  
RG204899 GFP-tagged ORF clone of Homo sapiens endothelin receptor type B (EDNRB), transcript variant 1 as transfection-ready DNA, 10µg
$580
 In Stock

$50 off anti-DDK and other anti-tag antibodies till June 30th, 2013

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Also for EDNRB (NM_000115)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RG204899
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence 		ORF Size: 1329 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: GPCRTransmembraneDruggable Genome
Protein Pathways: Calcium signaling pathwayNeuroactive ligand-receptor interactionMelanogenesis
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_000115.1, NP_000106
 RefSeq Size: 4286 RefSeq ORF: 1329
Synonyms : ABCDS; ET-B; ET-BR; ETB; ETBR; ETRB; HSCR; HSCR2; WS4A
LocusID: 1910 Cytogenetic: 13q22 Domains: 7tm_1
Summary: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan

 
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