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Home cDNA Clone TrueORF All XRCC6 ORF Clones

XRCC6 (NM_001469) Human cDNA ORF Clone

Specifications Citations (0) Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG204048 XRCC6 (GFP-tagged) - Human X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6), 10µg
$590
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for XRCC6 (NM_001469)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody
TrueORF Data for RG204048
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1830 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Transcription FactorsDruggable Genome
Protein Pathways: Non-homologous end-joining

Reference Data
RefSeq: NM_001469.3, NP_001460
RefSeq Size: 2156 RefSeq ORF: 1830
Synonyms : CTC75; CTCBF; G22P1; KU70; ML8; TLAA
LocusID: 2547 Cytogenetic: 22q13.2 Domains: SAP, Ku_C, Ku_N, ku
Summary: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008].

 

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