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Home cDNA Clone TrueORF All DVL2 ORF Clones

DVL2 (NM_004422) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG202233 DVL2 (GFP-tagged) - Human dishevelled, dsh homolog 2 (Drosophila) (DVL2), (10ug), 10µg
$590
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for RG202233
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 2211 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: ES Cell Differentiation/IPSDruggable Genome
Protein Pathways: Wnt signaling pathwayNotch signaling pathwayMelanogenesisPathways in cancerColorectal cancerBasal cell carcinoma
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_004422.2, NP_004413
RefSeq Size: 3046 RefSeq ORF: 2211
Synonyms : DSH homolog 2; dishevelled 2; dishevelled 2 (homologous to Drosophila dsh); segment polarity protein dishevelled homolog DVL-2; dishevelled, dsh homolog 2 (Drosophila)
LocusID: 1856 Cytogenetic: 17p13.1 Domains: DEP, DAX, PDZ, Dishevelled
Summary: This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008].

 

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