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 Home cDNA Clone TrueORF All ATP6AP1 ORF Clones

ATP6AP1 (NM_001183) Human cDNA ORF Clone

Western Blot Validated

Specifications Citations Clone of Other Species Product Documents
Cat. No. Description Price Availability  
RG200394 GFP-tagged ORF clone of Homo sapiens ATPase, H+ transporting, lysosomal accessory protein 1 (ATP6AP1) as transfection-ready DNA, 10µg
$590
 In Stock

$50 off anti-DDK and other anti-tag antibodies till June 30th, 2013

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Also for ATP6AP1 (NM_001183)
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TrueORF Data for RG200394
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence 		ORF Size: 1413 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Transmembrane
Protein Pathways: Oxidative phosphorylationMetabolic pathwaysLysosomeVibrio cholerae infectionEpithelial cell signaling in Helicobacter pylori infection
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_001183.3, NP_001174
 RefSeq Size: 2055 RefSeq ORF: 1413
Synonyms : 16A; Ac45; ATP6IP1; ATP6S1; CF2; VATPS1; XAP-3; XAP3
LocusID: 537 Cytogenetic: Xq28
Summary: This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. [provided by RefSeq, Jul 2008].

 
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