OriGene - DARS (NM_001349) Human ORF cDNA Clone

Western Blot Validated

TrueORF Data for RG200391

Vector:	pCMV6-AC-GFP Change vector?	Tag: C-terminal TurboGFP	Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Sequence Data:	ORF Nucleotide Sequence CHROMATOGRAMS Protein Sequence	ORF Size: 1506 bp Predicted Protein MW: 57 kDa
Restriction Sites:	SgfI-MluI Cloning Scheme for this gene Plasmid Map
OTI Annotation:	This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer:	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components:	The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families:
Protein Pathways:	Aminoacyl-tRNA biosynthesis

* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data

RefSeq: NM_001349.2, NP_001340	RefSeq Size: 2322	RefSeq ORF: 1506
Synonyms : DKFZp781B11202; MGC111579
LocusID: 1615	Cytogenetic: 2q21.3	Domains: tRNA-synt_2, tRNA_anti
Summary: Aspartyl-tRNA synthetase (DARS) is part of a multienzyme complex of aminoacyl-tRNA synthetases. Aspartyl-tRNA synthetase charges its cognate tRNA with aspartate during protein biosynthesis. [provided by RefSeq, Jul 2008].

ORF Clones Citations:

Solute Carrier 11A1 Is Expressed by Innate Lymphocytes and Augments Their Activation, Jodi F. Hedges, Emily Kimmel, Deann T. Snyder, Maria Jerome, and Mark A. Jutila, J. Immunol., Apr 2013; 190: 4263 - 4273. [SLC11A1]

A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function, Feng Gao, Hansel E. Ihn, Marisa W. Medina, and Ronald M. Krauss, Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [LDLR]

RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP, Lisa Muniz, Sylvain Egloff, and Tamás Kiss, Nucleic Acids Res., Apr 2013; 41: 4686 - 4698. [MEPCE ]

Structural basis for angiopoietin-1–mediated signaling initiation, Xuehong Yu, Tom C. M. Seegar, Annamarie C. Dalton, Dorothea Tzvetkova-Robev, Yehuda Goldgur, Kanagalaghatta R. Rajashankar, Dimitar B. Nikolov, and William A. Barton, PNAS, Apr 2013; 110: 7205 - 7210. [ANGPT1]

Inverted Formin 2 Regulates Actin Dynamics by Antagonizing Rho/Diaphanous-related Formin Signaling, Hua Sun, Johannes Schlondorff, Henry N. Higgs, and Martin R. Pollak, J. Am. Soc. Nephrol., Apr 2013; 10.1681/ASN.2012080834. [INF2]

MASL1 induces erythroid differentiation in human erythropoietin-dependent CD34+ cells through the Raf/MEK/ERK pathway, Chutima Kumkhaek, Wulin Aerbajinai, Wenli Liu, Jianqiong Zhu, Naoya Uchida, Roger Kurlander, Matthew M. Hsieh, John F. Tisdale, and Griffin P. Rodgers, Blood, Apr 2013; 121: 3216 - 3227. [MFHAS1 ]

Proximal tubule-dominant transfer of AT1a receptors induces blood pressure responses to intracellular angiotensin II in AT1a receptor-deficient mice, Xiao C. Li and Jia L. Zhuo, Am J Physiol Regulatory Integrative Comp Physiol, Apr 2013; 304: R588 - R598. [AGTR1A ]

DCNL1 Functions as a Substrate Sensor and Activator of Cullin 2-RING Ligase, Pardeep Heir, Roxana I. Sufan, Samantha N. Greer, Betty P. Poon, Jeffrey E. Lee, and Michael Ohh, Mol. Cell. Biol., Apr 2013; 33: 1621 - 1631. [DCNL1]

More TrueClone Citations >>

DARS Mouse Clones

SKU	Description	Amount	Price	Shipping
MC217054	Mus musculus aspartyl-tRNA synthetase (Dars), transcript variant 1 as transfection-ready DNA	10 ug	$600	4 weeks
MC212782	Mus musculus aspartyl-tRNA synthetase (Dars), transcript variant 2 as transfection-ready DNA	10 ug	$380	2 weeks
MR208055	Myc-DDK-tagged ORF clone of Mus musculus aspartyl-tRNA synthetase (Dars), transcript variant 1 as transfection-ready DNA	10 ug	$600	4 weeks
MR217423	Myc-DDK-tagged ORF clone of Mus musculus aspartyl-tRNA synthetase (Dars), transcript variant 2 as transfection-ready DNA	10 ug	$380	2 weeks
MG208055	GFP-tagged ORF clone of Mus musculus aspartyl-tRNA synthetase (Dars) in a GFP expression vector	10 ug	$660	3 weeks
MG217423	GFP-tagged ORF clone of Mus musculus aspartyl-tRNA synthetase (Dars) transcript variant 2 as transfection-ready DNA	10 ug	$420	3 weeks

DARS Rat Clones

SKU	Description	Amount	Price	Shipping
RN207016	NativeORF clone of Rattus norvegicus aspartyl-tRNA synthetase (Dars) as transfection-ready DNA	10 ug	$602	4 weeks
RR207016	Myc-DDK-tagged ORF clone of Rattus norvegicus aspartyl-tRNA synthetase (Dars) as transfection-ready DNA	10 ug	$602	4 weeks

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DARS (NM_001349) Human cDNA ORF Clone

Western Blot Validated

ORF Clones Citations:

DARS Mouse Clones

DARS Rat Clones

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