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Home cDNA Clone TrueORF All AADAT ORF Clones

AADAT (NM_016228) Human cDNA ORF Clone

Specifications Citations (3) Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG223277 AADAT (GFP-tagged) - Human aminoadipate aminotransferase (AADAT), transcript variant 1, 10µg   
$580
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TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
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0 2 weeks
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Also for AADAT (NM_016228)
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TrueORF Data for RG223277
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1275 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Pathways: Lysine biosynthesisLysine degradationTryptophan metabolismMetabolic pathways

Reference Data
RefSeq Explanation: NM_016228.3 , NP_057312
Synonyms: KAT2; KATII; KYAT2 RefSeq Size: 2326 RefSeq ORF: 1278
LocusID: 51166 Cytogenetic: 4q33
Gene Summary: This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2013].

 

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