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 Home cDNA Clone TrueORF All NMNAT1 ORF Clones

NMNAT1 (NM_022787) Human cDNA ORF Clone

Western Blot Validated

Specifications Citations Clone of Other Species Product Documents
Cat. No. Description Price Availability  
RG204825 GFP-tagged ORF clone of Homo sapiens nicotinamide nucleotide adenylyltransferase 1 (NMNAT1) as transfection-ready DNA, 10µg
$510
 2-3 weeks

$50 off anti-DDK and other anti-tag antibodies till June 30th, 2013

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Also for NMNAT1 (NM_022787)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RG204825
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence 		ORF Size: 840 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Pathways: Nicotinate and nicotinamide metabolismMetabolic pathways
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_022787.2, NP_073624
 RefSeq Size: 1825 RefSeq ORF: 840
Synonyms : LCA9; NMNAT; PNAT1
LocusID: 64802 Cytogenetic: 1p36.22 Domains: CTP_transf_2
Summary: This gene encodes an enzyme which catalyzes a key step in the biosynthesis of the coenzyme NAD. The encoded protein is one of several nicotinamide nucleotide adenylyltransferases. Studies in Drosophila and mammalian neurons have shown the encoded protein can confer protection to damaged neurons. This protection requires enzymatic activity which increases NAD levels and activates a nuclear deacetylase which is the protective molecule. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14 and 15. [provided by RefSeq, Dec 2011].

 
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