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 Home cDNA Clone TrueORF All GSTM4 ORF Clones

GSTM4 (NM_000850) Human cDNA ORF Clone

Western Blot Validated

Specifications Citations Clone of Other Species Product Documents
Cat. No. Description Price Availability  
RG202097 GFP-tagged ORF clone of Homo sapiens glutathione S-transferase mu 4 (GSTM4), transcript variant 1 as transfection-ready DNA, 10µg
$420
 In Stock

$50 off anti-DDK and other anti-tag antibodies till June 30th, 2013

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Also for GSTM4 (NM_000850)
cDNA Clone shRNA/siRNA Lysate Protein Antibody Service
TrueORF Data for RG202097
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence 		ORF Size: 657 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Pathways: Glutathione metabolismMetabolism of xenobiotics by cytochrome P450Drug metabolism - cytochrome P450
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_000850.3, NP_000841
 RefSeq Size: 1436 RefSeq ORF: 657
Synonyms : GSTM4-4; GTM4
LocusID: 2948 Cytogenetic: 1p13.3 Domains: GST_N, GST_C
Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified. [provided by RefSeq, Jul 2008].

 
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