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 Home cDNA Clone TrueORF All SHANK2 ORF Clones

SHANK2 (NM_133266) Human cDNA ORF Clone

Specifications Citations Clone of Other Species Product Documents
Cat. No. Description Price Availability  
RC229423 Myc-DDK-tagged ORF clone of Homo sapiens SH3 and multiple ankyrin repeat domains 2 (SHANK2), transcript variant 2 as transfection-ready DNA, 10µg
$1820
 5-6 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248
$198		 In Stock

$50 off anti-DDK and other anti-tag antibodies till June 30th, 2013

The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG229423 GFP-tagged ORF clone of Homo sapiens SH3 and multiple ankyrin repeat domains 2 (SHANK2), transcript variant 2 as transfection-ready DNA $2000 6 Weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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Also for SHANK2 (NM_133266)
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TrueORF Data for RC229423
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence 		ORF Size: 3786 bp
Predicted Protein MW: 135.5 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_133266.3, NP_573573
 RefSeq Size: RefSeq ORF: 3786
Synonyms : AUTS17; CORTBP1; CTTNBP1; ProSAP1; SHANK; SPANK-3
LocusID: 22941 Cytogenetic: 11q13.2
Summary: This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].

 
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