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Home cDNA Clone TrueORF All PROM1 ORF Clones

PROM1 (NM_001145852) Human cDNA ORF Clone

Specifications Citations Clone of Other Species Product Documents
Cat. No. Description Price Availability  
RC227954 Myc-DDK-tagged ORF clone of Homo sapiens prominin 1 (PROM1), transcript variant 4 as transfection-ready DNA, 10µg
$1190
4-5 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248
$198
In Stock

$50 off anti-DDK and other anti-tag antibodies till June 30th, 2013

The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG227954 GFP-tagged ORF clone of Homo sapiens prominin 1 (PROM1), transcript variant 4 as transfection-ready DNA $1310 5 Weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for RC227954
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 2478 bp
Predicted Protein MW: 92.6 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: ES Cell Differentiation/IPSTransmembraneDruggable Genome
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_001145852.1, NP_001139324
RefSeq Size: RefSeq ORF: 2478
Synonyms : AC133; CD133; CORD12; MCDR2; MSTP061; PROML1; RP41; STGD4
LocusID: 8842 Cytogenetic: 4p15.32
Summary: This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

 

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