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Home cDNA Clone TrueORF All CREM ORF Clones

CREM (NM_181571) Human cDNA ORF Clone

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Cat. No. Description Price Availability  
RC215303L2 Lenti ORF clone of Human cAMP responsive element modulator (CREM), transcript variant 1, mGFP tagged, 10µg   
$720
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TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC515303L2 0 2 weeks
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TrueORF Data for RC215303L2
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Vector: pLenti-C-mGFP   Change vector? Tag: C-terminal mGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 903 bp
Predicted Protein MW: 32.3 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Transcription FactorsDruggable Genome

Reference Data
RefSeq Explanation: NM_181571.1, NP_853549 RefSeq Size: 2225 RefSeq ORF: 903
Synonyms : CREM-2; hCREM-2; ICER
LocusID: 1390 Cytogenetic: 10p11.21
Gene Summary: This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008].

 

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