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Home cDNA Clone TrueORF All BMP2 ORF Clones

BMP2 (NM_001200) Human cDNA ORF Clone

Specifications Citations (5) Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC214586 BMP2 (Myc-DDK-tagged)-Human bone morphogenetic protein 2 (BMP2), 10µg   
$490
In Stock
RG214586 BMP2 (GFP-tagged) - Human bone morphogenetic protein 2 (BMP2) $550 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC514586 BMP2 (Myc-DDK-tagged)-Human bone morphogenetic protein 2 (BMP2), (200ug) $620 2 weeks
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Clone Modification
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The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG214586 BMP2 (GFP-tagged) - Human bone morphogenetic protein 2 (BMP2)

$550 In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for RC214586
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1188 bp
Predicted Protein MW: 44.63 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Stem cell relevant signaling - TGFb/BMP signaling pathwaySecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsCancer stem cellsEmbryonic stem cellsInduced pluripotent stem cellsDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionHedgehog signaling pathwayTGF-beta signaling pathwayPathways in cancerBasal cell carcinoma

Reference Data
RefSeq Explanation: NM_001200.1 NM_001200.2 NM_001200.3 , NP_001191
Synonyms: BDA2; BMP2A RefSeq Size: 1547 RefSeq ORF: 1191
LocusID: 650 Cytogenetic: 20p12.3 Domains: TGFb_propeptide, TGF-beta
Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]

 

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