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Home cDNA Clone TrueORF All GBA3 ORF Clones
TrueORF Gold

GBA3 (NM_020973) Human cDNA ORF Clone

Specifications Citations Clone of Other Species Product Documents
Cat. No. Description Price Availability  
RC211035 Myc-DDK-tagged ORF clone of Homo sapiens glucosidase, beta, acid 3 (cytosolic) (GBA3), transcript variant 1 as transfection-ready DNA, 10µg
$540
In Stock
RC511035 Myc-DDK-tagged ORF clone of Homo sapiens glucosidase, beta, acid 3 (cytosolic) (GBA3), transcript variant 1 as 200 ug transfection-ready DNA $660 2~3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248
$198
In Stock

$50 off anti-DDK and other anti-tag antibodies till June 30th, 2013

The same insert cloned in Lenti and other vectors is also available.

Cat. No. Description Vector Price Availability  
RC211035L1 Lenti ORF clone of Human glucosidase, beta, acid 3 (cytosolic) (GBA3), transcript variant 1 , Myc-DDK-tagged

$910 2 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $360 In Stock
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Also for GBA3 (NM_020973)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RC211035
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1410 bp
Predicted Protein MW: 53.5 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Pathways: Cyanoamino acid metabolismStarch and sucrose metabolism
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_020973.2, NP_066024
RefSeq Size: 2125 RefSeq ORF: 1410
Synonyms : CBGL1; GLUC; KLrP
LocusID: 57733 Cytogenetic: 4p15.2
Summary: GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).[supplied by OMIM, Mar

 

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