OriGene - SOX4 (NM_003107) Human ORF cDNA Clone

Western Blot Validated

The same insert cloned in a GFP-tagging vector is also available

Cat. No.	Description	Vector	Price	Availability
RG209139	GFP-tagged ORF clone of Homo sapiens SRY (sex determining region Y)-box 4 (SOX4) as transfection-ready DNA	pCMV6-AC-GFP	$590	In Stock
TA150041	2H8, Anti-tGFP monoclonal antibody, 100µl		$248	In Stock

TrueORF Data for RC209139

Vector:	pCMV6-Entry Change vector?	Tag: C-terminal Myc-DDK	Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Sequence Data:	ORF Nucleotide Sequence CHROMATOGRAMS Protein Sequence	ORF Size: 1425 bp Predicted Protein MW: 47.1 kDa
Restriction Sites:	SgfI-RsrII Cloning Scheme for this gene Plasmid Map
OTI Annotation:	This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer:	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components:	The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families:	Stem cell relevant signaling - TGFb/BMP signaling pathway ES Cell Differentiation/IPS Induced pluripotent stem cells Transcription Factors Druggable Genome
Protein Pathways:

* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data

RefSeq: NM_003107.2, NP_003098	RefSeq Size: 4912	RefSeq ORF: 1425
Synonyms : EVI16
LocusID: 6659	Cytogenetic: 6p22.3	Domains: HMG_box
Summary: This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008].

ORF Clones Citations:

Solute Carrier 11A1 Is Expressed by Innate Lymphocytes and Augments Their Activation, Jodi F. Hedges, Emily Kimmel, Deann T. Snyder, Maria Jerome, and Mark A. Jutila, J. Immunol., Apr 2013; 190: 4263 - 4273. [SLC11A1]

A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function, Feng Gao, Hansel E. Ihn, Marisa W. Medina, and Ronald M. Krauss, Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [LDLR]

RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP, Lisa Muniz, Sylvain Egloff, and Tamás Kiss, Nucleic Acids Res., Apr 2013; 41: 4686 - 4698. [MEPCE ]

Structural basis for angiopoietin-1–mediated signaling initiation, Xuehong Yu, Tom C. M. Seegar, Annamarie C. Dalton, Dorothea Tzvetkova-Robev, Yehuda Goldgur, Kanagalaghatta R. Rajashankar, Dimitar B. Nikolov, and William A. Barton, PNAS, Apr 2013; 110: 7205 - 7210. [ANGPT1]

Inverted Formin 2 Regulates Actin Dynamics by Antagonizing Rho/Diaphanous-related Formin Signaling, Hua Sun, Johannes Schlondorff, Henry N. Higgs, and Martin R. Pollak, J. Am. Soc. Nephrol., Apr 2013; 10.1681/ASN.2012080834. [INF2]

MASL1 induces erythroid differentiation in human erythropoietin-dependent CD34+ cells through the Raf/MEK/ERK pathway, Chutima Kumkhaek, Wulin Aerbajinai, Wenli Liu, Jianqiong Zhu, Naoya Uchida, Roger Kurlander, Matthew M. Hsieh, John F. Tisdale, and Griffin P. Rodgers, Blood, Apr 2013; 121: 3216 - 3227. [MFHAS1 ]

Proximal tubule-dominant transfer of AT1a receptors induces blood pressure responses to intracellular angiotensin II in AT1a receptor-deficient mice, Xiao C. Li and Jia L. Zhuo, Am J Physiol Regulatory Integrative Comp Physiol, Apr 2013; 304: R588 - R598. [AGTR1A ]

DCNL1 Functions as a Substrate Sensor and Activator of Cullin 2-RING Ligase, Pardeep Heir, Roxana I. Sufan, Samantha N. Greer, Betty P. Poon, Jeffrey E. Lee, and Michael Ohh, Mol. Cell. Biol., Apr 2013; 33: 1621 - 1631. [DCNL1]

More TrueClone Citations >>

SOX4 Mouse Clones

SKU	Description	Amount	Price	Shipping
MC215803	Mus musculus SRY-box containing gene 4 (Sox4) as transfection-ready DNA	10 ug	$530	4 weeks
MR207005	Myc-DDK-tagged ORF clone of Mus musculus SRY-box containing gene 4 (Sox4) as transfection-ready DNA	10 ug	$530	Next day
MG207005	GFP-tagged ORF clone of Mus musculus SRY-box containing gene 4 (cDNA clone MGC:64652 IMAGE:6822618) in a GFP expression vector	10 ug	$580	Next day

Don't see the species of your interest?
Use Blue Heron gene synthesis and make clone in any of OriGene's expression vectors.

All Products by:	Title \| Price \| Category \| Popularity \| Best Sellers	Topselling Products by:	Title \| Price \| Category \| Popularity \| Favorites
Popular Categories:	Popularity \| Our Choices \| All-Round Favorites \| Title	Topselling Categories:	Popularity \| Our Choices \| All-Round Favorites \| Title

SOX4 (NM_003107) Human cDNA ORF Clone

Western Blot Validated

ORF Clones Citations:

SOX4 Mouse Clones

Product Manuals

MSDS

FAQs