OriGene - ATP2A2 (NM_170665) Human ORF cDNA Clone

ATP2A2 (NM_170665) Human cDNA ORF Clone

TrueORF Data for RC207626

Vector:	pCMV6-Entry Change vector?	Tag: C-terminal Myc-DDK	Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Sequence Data:	ORF Nucleotide Sequence CHROMATOGRAMS Protein Sequence	ORF Size: 3129 bp Predicted Protein MW: 114.6 kDa
Restriction Sites:	SgfI-MluI Cloning Scheme for this gene Plasmid Map
OTI Annotation:	This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer:	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components:	The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families:	Transmembrane Druggable Genome
Protein Pathways:	Calcium signaling pathway Cardiac muscle contraction Alzheimer's disease Hypertrophic cardiomyopathy (HCM)Arrhythmogenic right ventricular cardiomyopathy (ARVC)Dilated cardiomyopathy

* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data

RefSeq: NM_170665.2, NP_733765	RefSeq Size: 4205	RefSeq ORF: 3129
Synonyms : ATP2B; DAR; DD; SERCA2
LocusID: 488	Cytogenetic: 12q24.11	Domains: E1-E2_ATPase, Cation_ATPase_N, Hydrolase, Cation_ATPase_C
Summary: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008].

SKU	Description	Amount	Price	Shipping
MC223036	Mus musculus ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (Atp2a2), transcript variant 2 as transfection-ready DNA	10 ug	$1200	Next day
MC223305	Mus musculus ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (Atp2a2), transcript variant 1 as transfection-ready DNA	10 ug	$1250	6 weeks
MR211518	Myc-DDK-tagged ORF clone of Mus musculus ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (Atp2a2), transcript variant 1 as transfection-ready DNA	10 ug	$1250	6 weeks
MR226794	Myc-DDK-tagged ORF clone of Mus musculus ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (Atp2a2), transcript variant 2 as transfection-ready DNA	10 ug	$1200	6 weeks
MG211518	GFP-tagged ORF clone of Mus musculus ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (cDNA clone MGC:62264 IMAGE:6406916) in a GFP expression vector	10 ug	$1380	4 weeks
MG226794	GFP-tagged ORF clone of Mus musculus ATPase Ca++ transporting cardiac muscle slow twitch 2 (Atp2a2) transcript variant 2 as transfection-ready DNA	10 ug	$1320	Next day

SKU	Description	Amount	Price	Shipping
RN200367	NativeORF clone of Rattus norvegicus ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (Atp2a2), transcript variant 2 as transfection-ready DNA	10 ug	$1198	6 weeks
RN200368	NativeORF clone of Rattus norvegicus ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (Atp2a2), transcript variant 3 as transfection-ready DNA	10 ug	$1566	6 weeks
RR200367	Myc-DDK-tagged ORF clone of Rattus norvegicus ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (Atp2a2), transcript variant 2 as transfection-ready DNA	10 ug	$1198	6 weeks
RR200368	Myc-DDK-tagged ORF clone of Rattus norvegicus ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (Atp2a2), transcript variant 3 as transfection-ready DNA	10 ug	$1566	6 weeks

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ATP2A2 (NM_170665) Human cDNA ORF Clone