Money Format Issue: Input string was not in a correct format. OriGene - CASP4 (NM_033306) Human ORF cDNA Clone
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CASP4 (NM_033306) Human cDNA ORF Clone

Western Blot Validated

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC204711L2 Lenti ORF clone of Human caspase 4, apoptosis-related cysteine peptidase (CASP4), transcript variant gamma, mGFP tagged, 10µg
2-3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for RC204711L2
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Vector: pLenti-C-mGFP   Change vector? Tag: C-terminal mGFP
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 966 bp
Predicted Protein MW: 36.5 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: ProteaseDruggable Genome

Reference Data
RefSeq: NM_033306.2, NP_150649
RefSeq Size: 1352 RefSeq ORF: 0
Synonyms : ICE(rel)II; ICEREL-II; ICH-2; Mih1/TX; TX
LocusID: 837 Cytogenetic: 11q22.2-q22.3 Domains: CASc, ICE_p10, ICE_p20
Summary: This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].

 

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