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Home cDNA Clone TrueORF All OAS1 ORF Clones
TrueORF Gold

OAS1 (NM_002534) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC200696 OAS1 (Myc-DDK-tagged)-Human 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2, 10µg   
$560
In Stock
RG200696 OAS1 (GFP-tagged) - Human 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2, (10ug) $610 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC500696 OAS1 (Myc-DDK-tagged)-Human 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2, (200ug) $680 2 weeks
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Clone Modification
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The same insert cloned in Lenti and other vectors are also available.

Cat. No. Description Vector Price Availability  
RC200696L1 Lenti ORF clone of Human 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2 , Myc-DDK-tagged

$740 3 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
Lenti particle icon Add to Shopping Cart
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TrueORF Data for RC200696
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1095 bp
Predicted Protein MW: 41.6 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Druggable Genome
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq Explanation: NM_002534.2, NP_002525 RefSeq Size: 1470 RefSeq ORF: 1095
Synonyms : IFI-4; OIAS; OIASI
LocusID: 4938 Cytogenetic: 12q24.2
Gene Summary: This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12. [provided by RefSeq, Feb 2016].

 

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