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Home cDNA Clone TrueORF All APOE ORF Clones
TrueORF Gold

APOE (NM_000041) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC200395 APOE (Myc-DDK-tagged)-Human apolipoprotein E (APOE), 10µg   
470
$98
In Stock
RG200395 APOE (GFP-tagged) - Human apolipoprotein E (APOE), (10ug) $530 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC500395 APOE (Myc-DDK-tagged)-Human apolipoprotein E (APOE), (200ug) $600 2 weeks
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Clone Modification
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The same insert cloned in Lenti and other vectors are also available.

Cat. No. Description Vector Price Availability  
RC200395L1 Lenti ORF clone of Human apolipoprotein E (APOE) , Myc-DDK-tagged

$660 3 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
Lenti particle icon Add to Shopping Cart
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TrueORF Data for RC200395
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 954 bp
Predicted Protein MW: 36.15 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Secreted ProteinStem cell - PluripotencyAdult stem cellsDruggable Genome
Protein Pathways: Alzheimer's disease
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq Explanation: NM_000041.2, NP_000032 RefSeq Size: 1223 RefSeq ORF: 954
Synonyms : AD2; APO-E; LDLCQ5; LPG
LocusID: 348 Cytogenetic: 19q13.2 Domains: Apolipoprotein
Gene Summary: The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014].

 

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