OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431.
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780.
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210.
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Home Gene of the month BRAF|
BRAF – Protein Kinase
The BRAF gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. BRAF plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. BRAF mutations are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. In addition, BRAF mutations have been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung.
OriGene offers the following BRAF related products
||BRAF Antibodies – TrueMABTM, extensively validated monoclonal antibodies|
TA500852 – WB, IHC, IF, FC reacts with Human
TA600011 – ELISA reacts with Human
More BRAF Antibodies
||BRAF Protein – Full length human BRAF protein|
TP311013 – BIOACTIVE!!! Expressed in HEK293 cells
||BRAF ORF clones – transfection ready DNA|
RC211013 – MYC-DDK tagged clone
SC126575 – untagged clone
|TR320276 – BRAF shRNA, performance guarantee|
SR300470 – BRAF siRNA, performance guarantee
For all 35 BRAF products please click here!