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Home CRISPR-CAS9 KN301872

Aurkb - mouse gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN301872 Aurkb - mouse gene knockout kit via CRISPR $1200 4 weeks Manual PDF Add to Shopping Cart
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Also for Aurkb (Locus ID 20877)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Request Antibody
SKU Description Donor Vector Price Availability  
KN301872RB Aurkb - mouse gene knockout kit via CRISPR RFP-BSD 1290 4 weeks
KN301872LP Aurkb - mouse gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN301872BN Aurkb - mouse gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
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Comparing to KN301872, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN301872G1, Aurkb gRNA vector 1 in pCas-Guide vector
KN301872G2, Aurkb gRNA vector 2 in pCas-Guide vector
KN301872D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: BC003261NM_011496
Synonyms: Aik2; AIM-1; Aim1; AIRK2; AL022959; Ark2; AurB; IPL1; STK-1; Stk12; Stk5
Summary: This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 2 and 7. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. [provided by RefSeq, Sep 2015].

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Diagram-Gene Editing RecombII


 

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