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Home CRISPR-CAS9 KN221316

SPANXD - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN221316 SPANXD - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN221316RB SPANXD - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN221316LP SPANXD - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN221316BN SPANXD - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN221316, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
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Kit Components
KN221316G1, SPANXD gRNA vector 1 in pCas-Guide vector
KN221316G2, SPANXD gRNA vector 2 in pCas-Guide vector
KN221316D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_032417
Synonyms: CT11.4; dJ171K16.1; SPANX-C; SPANX-D; SPANX-E; SPANXE
Summary: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that is associated with the nucleus but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined. Polymorphisms in this gene may be associated with prostate cancer susceptibility. [provided by RefSeq, Apr 2014]

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Diagram-Gene Editing RecombII


 

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