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Home CRISPR-CAS9 KN219975

LASP1 - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN219975 LASP1 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN219975RB LASP1 - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN219975LP LASP1 - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN219975BN LASP1 - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN219975, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN219975G1, LASP1 gRNA vector 1 in pCas-Guide vector
KN219975G2, LASP1 gRNA vector 2 in pCas-Guide vector
KN219975D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_001271608NM_006148NR_073384
Synonyms: Lasp-1; MLN50
Summary: This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012]

Learn more about CRISPR?

Diagram-Gene Editing RecombII


 

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