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Home CRISPR-CAS9 KN214164

PDGFA - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN214164 PDGFA - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN214164RB PDGFA - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN214164LP PDGFA - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN214164BN PDGFA - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN214164, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN214164G1, PDGFA gRNA vector 1 in pCas-Guide vector
KN214164G2, PDGFA gRNA vector 2 in pCas-Guide vector
KN214164D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_002607NM_033023XM_011515415XM_011515416XM_011515417XM_011515418XM_011515419XM_017012289
Synonyms: PDGF-A; PDGF1
Summary: This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

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Diagram-Gene Editing RecombII


 

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