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Home CRISPR-CAS9 KN210943

TXLNG - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN210943 TXLNG - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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Also for TXLNG (Locus ID 55787)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Request Antibody
SKU Description Donor Vector Price Availability  
KN210943RB TXLNG - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN210943LP TXLNG - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN210943BN TXLNG - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN210943, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN210943G1, TXLNG gRNA vector 1 in pCas-Guide vector
KN210943G2, TXLNG gRNA vector 2 in pCas-Guide vector
KN210943D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_001168683NM_018360XM_017029631XR_001755710
Synonyms: CXorf15; ELRG; FIAT; LSR5; TXLNGX
Summary: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].

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Diagram-Gene Editing RecombII


 

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