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Home CRISPR-CAS9 KN210267

TRIM63 - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN210267 TRIM63 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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Also for TRIM63 (Locus ID 84676)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Request Antibody
SKU Description Donor Vector Price Availability  
KN210267RB TRIM63 - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN210267LP TRIM63 - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN210267BN TRIM63 - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN210267, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN210267G1, TRIM63 gRNA vector 1 in pCas-Guide vector
KN210267G2, TRIM63 gRNA vector 2 in pCas-Guide vector
KN210267D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_032588XM_017002559
Synonyms: IRF; MURF1; MURF2; RNF28; SMRZ
Summary: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]

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Diagram-Gene Editing RecombII


 

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