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Home CRISPR-CAS9 KN210103

ALKBH2 - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN210103 ALKBH2 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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Also for ALKBH2 (Locus ID 121642)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Request Antibody
SKU Description Donor Vector Price Availability  
KN210103RB ALKBH2 - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN210103LP ALKBH2 - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN210103BN ALKBH2 - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN210103, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN210103G1, ALKBH2 gRNA vector 1 in pCas-Guide vector
KN210103G2, ALKBH2 gRNA vector 2 in pCas-Guide vector
KN210103D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_001001655NM_001145374NM_001145375NM_001205179NM_001205180NR_026930NR_026931XM_005253835XM_005253836
Synonyms: ABH2; ABH2
Summary: The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008].

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