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Home CRISPR-CAS9 KN209411

FBXW4 - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN209411 FBXW4 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN209411RB FBXW4 - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN209411LP FBXW4 - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN209411BN FBXW4 - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN209411, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN209411G1, FBXW4 gRNA vector 1 in pCas-Guide vector
KN209411G2, FBXW4 gRNA vector 2 in pCas-Guide vector
KN209411D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: AK056917NM_022039XM_005270053XM_017016570
Synonyms: DAC; FBW4; FBWD4; SHFM3; SHSF3
Summary: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling. [UniProtKB/Swiss-Prot Function]

Learn more about CRISPR?

Diagram-Gene Editing RecombII


 

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