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Home CRISPR-CAS9 KN207777

GIF - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN207777 GIF - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN207777RB GIF - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN207777LP GIF - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN207777BN GIF - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN207777, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
kn_donor_diagram
Kit Components
KN207777G1, GIF gRNA vector 1 in pCas-Guide vector
KN207777G2, GIF gRNA vector 2 in pCas-Guide vector
KN207777D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_005142XM_011544939
Synonyms: IF; IFMH; INF; TCN3
Summary: Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis. [UniProtKB/Swiss-Prot Function]

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Diagram-Gene Editing RecombII


 

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