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Home CRISPR-CAS9 KN201114

CDH15 - human gene knockout kit via CRISPR

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Specifications  Citations  Validation Data  FAQ
SKU Description Price Availability Manual  
KN201114 CDH15 - human gene knockout kit via CRISPR $1200 4 Weeks Manual PDF Add to Shopping Cart
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SKU Description Donor Vector Price Availability  
KN201114RB CDH15 - human gene knockout kit via CRISPR RFP-BSD 1290 4 Weeks
KN201114LP CDH15 - human gene knockout kit via CRISPR Luciferase-Puro 1290 4 Weeks
KN201114BN CDH15 - human gene knockout kit via CRISPR mBFP-Neo 1290 4 Weeks
Add to Shopping Cart

Comparing to KN201114, the above kits contain:

  • Identical gRNA vectors
  • Identical LHA & RHA
  • Different donor cassette
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Kit Components
KN201114G1, CDH15 gRNA vector 1 in pCas-Guide vector
KN201114G2, CDH15 gRNA vector 2 in pCas-Guide vector
KN201114D, donor vector containing Left and right homologous arms and GFP-Puro functional cassette.
   
GE100003, scramble sequence in pCas-Guide vector

Disclaimer
The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data
RefSeq: NM_004933
Synonyms: CDH14; CDH3; CDHM; MCAD; MRD3
Summary: This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq, Jul 2008].

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Diagram-Gene Editing RecombII


 

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