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Home Antibody All anti-ATP6AP1 antibodies
UltraMAB

Anti-ATP6AP1 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA590072 Rabbit Polyclonal ATP6AP1 Antibody 100ug $325 In Stock
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WB(1)
IHC(4)

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the Middle Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.23mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:20000, IHC 1:150,ELISA 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens ATPase, H+ transporting, lysosomal accessory protein 1 (ATP6AP1)
Alternative Name16A; Ac45; ATP6IP1; ATP6S1; CF2; VATPS1; XAP-3; XAP3
Database LinkNP_001174
Entrez Gene 537 Human
FunctionThis gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules.
Related PathwayTransmembrane Oxidative phosphorylationMetabolic pathwaysLysosomeVibrio cholerae infectionEpithelial cell signaling in Helicobacter pylori infection

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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATP6AP1 (RC200394, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATP6AP1.
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Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-ATP6AP1 Rabbit Polyclonal antibody. (TA590072)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-ATP6AP1 Rabbit Polyclonal antibody. (TA590072)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-ATP6AP1 Rabbit Polyclonal antibody. (TA590072)
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Immunohistochemistry: ATP6AP1 Antibody - Most of the normal tissues displayed moderate to strong cytoplasmic positivity which was occasionally combined with membranous and nuclear staining. Malignant tissues generally displayed moderate cytoplasmic immunoreactivity. Many cases of malignant gliomas exhibited strong staining which also was observed in occasional other tumors. Image and statement courtesy of the Human Protein Atlas (HPA).
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