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Anti-ENG TRUEMAB Antibody Clone OTI6G8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA506144 ENG (CD105) mouse monoclonal antibody, clone OTI6G8 (formerly 6G8) 100ul 325
In Stock
LC424919 ENG HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506144 Carrier-free (BSA/glycerol-free) ENG mouse monoclonal antibody, clone OTI6G8 (formerly 6G8) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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OriGene Data

ImmunogenFull length human recombinant protein of human ENg(NP_000109) produced in HEK293T cell.
Clone NameClone OTI6G8 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF Suggested Dilutions WB 1:2000, IF 1:100,
Predicted MW Explanation 65 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens endoglin (ENG), transcript variant 2
Alternative NameEND; HHT1; ORW1
Database LinkNP_000109
Entrez Gene 2022 Human
FunctionThis gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ENG (RC221699, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ENG.
Immunofluorescent staining of HeLa cells using anti-ENG mouse monoclonal antibody (TA506144).


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