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Anti-GCK TRUEMAB Antibody clone 3E3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500459
  • GCK mouse monoclonal antibody, clone 3E3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400059) , 20ug
100ul 379 In Stock
CF500459
  • Carrier-free (BSA/glycerol-free) GCK mouse monoclonal antibody, clone 3E3
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(9)
IF(1)
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Also for GCK (NM_000162)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human GCK (NP_000153) produced in HEK293T cell.
Clone Nameclone 3E3 IsotypeIgG1
Species ReactivityHuman Concentration1.00mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:500, IHC 1:50, IF 1:50,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens glucokinase (hexokinase 4) (GCK), transcript variant 1
Alternative NameFGQTL3; GK; GLK; HHF3; HK4; HKIV; HXKP; LGLK; MODY2
Database LinkNP_000153
FunctionHexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq].
Related Pathway
MAPK signaling pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GCK (RC200472, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GCK.
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-GCK mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-GCK mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-GCK mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-GCK mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-GCK mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-GCK mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-GCK mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-GCK mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-GCK mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500459)
IF Image
Anti-GCK mouse monoclonal antibody (TA500459) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GCK(RC200472).

 

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