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Anti-NTRK2 TRUEMAB Antibody Clone OTI2E1
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for NTRK2 (NM_001007097)
|Full-length protein expressed in 293T cell transfected with human NTRK2 expression vector|
|WB, IHC, IF
||WB 1:1000, IHC 1:150, IF 1:100,
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant b|
|GP145-TrkB; trk-B; TRKB|
Entrez Gene 4915 Human
|This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene|
|Protein KinaseTransmembraneDruggable Genome MAPK signaling pathwayNeurotrophin signaling pathway|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NTRK2 (RC205129, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NTRK2.
Immunohistochemical staining of paraffin-embedded Human lung tissue within the normal limits using anti-NTRK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500386)
Anti-NTRK2 mouse monoclonal antibody (TA500386) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NTRK2(RC205129).