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Home Antibody All anti-HES1 antibodies

Anti-HES1 TRUEMAB Antibody Clone OTI4H1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500114 anti-HES1 mouse monoclonal antibody, clone OTI4H1 (formerly 4H1) 100ul
30ul
$379 In Stock
LC417251 HES1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500114 Carrier-free (BSA/glycerol-free) HES1 mouse monoclonal antibody, clone OTI4H1 (formerly 4H1) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(5)
IF(2)

OriGene Data

ImmunogenRecombinant protein expressed in E.coli corresponding to amino acids 1-280 of human HES1
Clone NameClone OTI4H1 IsotypeIgG1
Species ReactivityHuman Concentration0.52 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:1000; IHC 1:50; RPPA 1:75; IF (1:100)
Predicted MW Explanation 29.4 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Reference Data

Target NameHomo sapiens hes family bHLH transcription factor 1 (HES1)
Alternative NamebHLHb39; HES-1; HHL; HRY
Database LinkNP_005515
Entrez Gene 3280 Human
FunctionThis protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
Related PathwayStem cell relevant signaling - DSL/Notch pathwayES Cell Differentiation/IPSAdult stem cellsCancer stem cellsTranscription FactorsDruggable Genome Notch signaling pathwayMaturity onset diabetes of the young

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HES1(RC211709) (RC211709, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1.
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Immunohistochemical staining of paraffin-embedded breast within the normal limits using anti-HES1 (TA000114) mouse monoclonal antibody (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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Immunohistochemical staining of paraffin-embedded kidney within the normal limits using anti-HES1 (TA500114) mouse monoclonal antibody (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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Immunohistochemical staining of paraffin-embedded liver within the normal limits using anti-HES1 (TA500114) mouse monoclonal antibody (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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Immunohistochemical staining of paraffin-embedded Carcinoma of liver using anti-HES1 (TA500114) mouse monoclonal antibody (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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Immunohistochemical staining of paraffin-embedded endometrium within the normal limits using anti-HES1 (TA500114) mouse monoclonal antibody (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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Anti-HES1 mouse monoclonal antibody (TA500114) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HES1(RC211709).
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Immunofluorescent staining of HeLa cells using anti-HES1 mouse monoclonal antibody (TA500114).
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