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Home Antibody All anti-AFGF antibodies

Anti-AFGF TRUEMAB Antibody Clone OTI4D2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500064 aFGF (FGF1) mouse monoclonal antibody, clone OTI4D2 (formerly 4D2) 100ul $379 In Stock
LC400278 FGF1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500064 Carrier-free (BSA/glycerol-free) aFGF mouse monoclonal antibody, clone OTI4D2 (formerly 4D2) 100ug $450 3-4 weeks
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WB(2)
IF(1)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 16-155 of human AFGF (NP_000791) produced in E.coli.
Clone NameClone OTI4D2 IsotypeIgG1
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:5000~50000, IF 1:100,
Predicted MW Explanation 15.8 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens fibroblast growth factor 1 (acidic) (FGF1), transcript variant 1
Alternative NameAFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-1; FGF-alpha; FGFA; GLIO703; HBGF-1; HBGF1
Database LinkNP_000791
Entrez Gene 2246 Human
FunctionFGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described.
Related PathwaySecreted ProteinDruggable Genome MAPK signaling pathwayRegulation of actin cytoskeletonPathways in cancerMelanoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AFGF (RC207434, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AFGF.
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aFGF antibody ( 4D2 ) at 1:50000 dilution + recombinant Human aFGF (Cat# RC207434)
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Anti-AFGF mouse monoclonal antibody (TA500064) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY AFGF(RC207434).
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