NRG4 Rabbit Polyclonal Antibody

CAT#: TA349574

Rabbit Polyclonal Anti-NRG4 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA349574 (NRG4 Antibody) at dilution 1/60 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA349574 (NRG4 Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349574 (NRG4 Antibody) at dilution 1/60 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349574 (NRG4 Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human NRG4
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: neuregulin 4
• Database Link:
  NP_612640
  Entrez Gene 145957 Human
  UniProt ID Q8WWG1
• Background: Neuregulin 4 also known as NRG4 is a member of the neuregulin protein family which in humans is encoded by theNRG4 gene. Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors.
• Synonyms: HRG4

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: ErbB signaling pathway