Home Antibody All anti-PTCRA antibodies
Also for PTCRA (NM_138296)
|Synthetic peptide surrounding amino acid 138 of human TCRa|
|Human, mouse, rat
||WB: 0.5-4 ug/ml, IHC: 15-25 ug/ml, IP: 10-20 ug/ml
|100 mg (0.2 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens pre T-cell antigen receptor alpha (PTCRA), transcript variant 2|
Entrez Gene 171558 Human
Entrez Gene 19208 Mouse
Entrez Gene 116462 Rat
|TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either a and ß or ? and d chains. The vast majority of circulating T cells (95%) express the a/ß heterodimer while roughly 2-5% express the ?/d heterodimer. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction through the TCR. |
|Transmembrane Notch signaling pathway|
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Western blot analysis of TCR-alpha expression in Jurkat cell lysate.