Home Antibody All anti-CRIM1 antibodies
Also for CRIM1 (NM_016441)
|CRIM1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Crim1.|
||WB: 1-2 ug/ml, ELISA
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Affinity chromatography purified via peptide column
|Homo sapiens cysteine rich transmembrane BMP regulator 1 (chordin-like) (CRIM1)|
|CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.|
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Western blot analysis of CRIM1 in Jurkat cell lysate with Crim1 antibody at 1 µg/ml.