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Home Antibody All anti-CRIM1 antibodies

Anti-CRIM1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319055
  • Rabbit polyclonal anti-CRIM1 antibody (CT)
100ug 345 3-7 Days
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WB(1)

OriGene Data

ImmunogenCRIM1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Crim1.
Clone Name IsotypeRabbit IgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-2 ug/ml, ELISA
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens cysteine rich transmembrane BMP regulator 1 (chordin-like) (CRIM1)
Alternative NameCRIM-1; S52
Database LinkNP_057525
Entrez Gene 51232 Human
FunctionCRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.
Related PathwaySecreted ProteinTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of CRIM1 in Jurkat cell lysate with Crim1 antibody at 1 µg/ml.

 

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