Home Antibody All anti-St14 antibodies
Also for St14 (NM_021978)
|Synthetic peptide surrounding amino acid 629 of rat Matriptase|
|Human, mouse, rat
||WB: 0.5-4 ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens suppression of tumorigenicity 14 (colon carcinoma) (ST14)|
|ARCI11; HAI; MT-SP1; MTSP1; PRSS14; SNC19; TADG15; TMPRSS14|
Entrez Gene 6768 Human
Entrez Gene 19143 Mouse
Entrez Gene 114093 Rat
|Matriptase or MT-SP1 is an epithelial-derived type II transmembrane serine protease that is highly expressd in human cancer-derived cell lines. Matriptase cleaves and activates protease activated receptor-2, pro-urokinase plasminogen activator and pro-hepatocyte growth factor. Matriptase is strongly inhibited by the hepatocyte growth factor activator inhibitor type 1 (HAI-1), which is a reactive site loop of Kunitz domain and also a transmembrane serine protease inhibitor.|
|TransmembraneProteaseDruggable Genome |
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Western blot analysis of Matriptase expression with Jurkat cell lysate.