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Home Antibody All anti-Plaur antibodies

Anti-Plaur Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318957
  • Rabbit polyclonal anti-uPAR antibody
100ug 325 In Stock
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WB(1)
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Also for Plaur (NM_002659)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 51 of rat uPAR
Clone Name IsotypeRabbit IgG
Species ReactivityRat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 0.5-1 ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in 1X phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens plasminogen activator, urokinase receptor (PLAUR), transcript variant 1
Alternative NameCD87; U-PAR; UPAR; URKR
Database LinkNP_002650
FunctionuPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum ß-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.
Related Pathway
Hemostasis

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WB Image
Western blot analysis of uPAR expression in rat kidney tissue lysate.

 

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