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Home Antibody All anti-RGS3 antibodies

Anti-RGS3 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA318896 Rabbit polyclonal anti-RGS3 antibody 100ug $325 3-7 Days
LC402835 RGS3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenE. coli-expressed human RGS3
Clone Name IsotypeRabbit IgG
Species ReactivityHuman Concentration0.2 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1ug/ml, IP
Buffer100 µg (0.2 mg/ml) protein A-purified rabbit anti-RGS3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.
Purification Affinity purified

Reference Data

Target NameHomo sapiens regulator of G-protein signaling 3 (RGS3), transcript variant 2
Alternative NameC2PA; PDZ-RGS3; RGP3
Database LinkNP_066929
Entrez Gene 5998 Human
FunctionRGS3 (regulator of G protein signaling 3) is a 519-residue protein that is widely expressed in many tissues and cells. The protein contains an RGS domain near the carboxy terminus that serves as a GTPase-activating protein (GAP). RGS3 negatively regulates the activation of Gia and Gaq. A truncated RGS3 (RGS3T), with its N-terminal 313 residues removed, has been shown to negatively regulate acenylyl cyclase and PLC. RGS3T may be localized in the nucleus and RGS3 is found in cytoplasm. Translocation to membrane is important for the RGS proteins to interact with heterotrimeric G proteins.
Related PathwayDruggable Genome Axon guidance

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of RGS3 in transfected HEK293 cells (right lane).
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