Home Antibody All anti-RGS3 antibodies
Also for RGS3 (NM_021106)
|E. coli-expressed human RGS3|
||WB: 1ug/ml, IP
|100 µg (0.2 mg/ml) protein A-purified rabbit anti-RGS3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.|
|Homo sapiens regulator of G-protein signaling 3 (RGS3), transcript variant 2|
|C2PA; PDZ-RGS3; RGP3|
Entrez Gene 5998 Human
|RGS3 (regulator of G protein signaling 3) is a 519-residue protein that is widely expressed in many tissues and cells. The protein contains an RGS domain near the carboxy terminus that serves as a GTPase-activating protein (GAP). RGS3 negatively regulates the activation of Gia and Gaq. A truncated RGS3 (RGS3T), with its N-terminal 313 residues removed, has been shown to negatively regulate acenylyl cyclase and PLC. RGS3T may be localized in the nucleus and RGS3 is found in cytoplasm. Translocation to membrane is important for the RGS proteins to interact with heterotrimeric G proteins. |
|Druggable Genome Axon guidance|
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Western blot analysis of RGS3 in transfected HEK293 cells (right lane).