OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-PPP3CB antibodies

Anti-PPP3CB Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318865
  • Rabbit polyclonal anti-Calcineurin A antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC412072) , 20ug
100ug 325 3-7 Days
Add to Shopping Cart
WB(1)
spacer
Also for PPP3CB (NM_021132)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to residues surrounding amino acids 267 of human Calcineurin A
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat, hamster, rabbit, bovine Concentration0.2 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-4ug/ml, IP: 10-20ug/ml
Buffer100 µg (0.2 mg/ml) affinity purified, rabbit anti-Calcineurin A polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens protein phosphatase 3, catalytic subunit, beta isozyme (PPP3CB), transcript variant 2
Alternative NameCALNA2; CALNB; CNA2; PP2Bbeta
Database LinkNP_066955
FunctionCalcineurin is a calcium/calmodulin-dependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit of 61 kDa and a myristylated regulatory B subunit of 19 kDa that binds calcium. The catalytic A subunit consists of an amino terminal catalytic domain, followed by calmodulin and B subunit binding sites, and a caboxyl-terminal autoinhibitory domain. Calnineurin is the target of immunosuppressant drugs such as cyclosporin A and FK506. Calcineurin controls the translocation of nuclear factors of activated T cells (NFAT), a family of transcriptional activators that control the expression of cytokine genes essential to immune response, from the cytosol into the nucleus of activated T cells. Calcineurin has been proposed to play an important role in mediating calcium-activated cell death.
Related Pathway
MAPK signaling pathway
Wnt Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Calcineurin A in lysate from Jurkat cells (Lane 1) and rat kidney (Lane 2).

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title