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Anti-TXN Antibody EPR6111


Specifications Citations (1) Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA311099 Rabbit Monoclonal antibody against Thioredoxin 1 (TXN) 100ul $325 2 Weeks
LC418748 TXN HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Thioredoxin 1 was used as an immunogen.
Clone NameEPR6111 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, Assay, IP Suggested DilutionsWB: 1:10000 - 1:50000; FC: 1:10 - 1:100
Predicted MW Explanation 12 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens thioredoxin (TXN), transcript variant 1
Alternative NameTRDX; TRX; TRX1
Database LinkNP_003320
Entrez Gene 7295 Human
FunctionThioredoxin 1 is a 12-kD oxidoreductase enzyme containing a dithiol-disulfide active site. It is ubiquitous and found in many organisms from plants and bacteria to mammals. Multiple in vitro substrates for thioredoxin 1 have been identified, including ribonuclease, choriogonadotropins, coagulation factors, glucocorticoid receptor, and insulin. Reduction of insulin is classically used as an activity test (1).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Thioredoxin / TRX antibody [EPR6111]; All lanes : Anti-Thioredoxin / TRX antibody [EPR6111] at 1/10000 dilution.Lane 1 : MCF-7 cell lysate.Lane 2 : THP-1 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : HepG2 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 12 kDa.

Assay Image
Other-Anti-Thioredoxin / TRX antibody [EPR6111](TA311099); Equilibrium disassociation constant (KD)..

IP Image
Figure from citation: Immunoprecipitation of Trx1 protein level by using anti-Trx1 antibody in rat myocardial tissue at week 12 after STZ injection. View Citation


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