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Home Antibody All anti-SLC9A3R1 antibodies

Anti-SLC9A3R1 Antibody EPR5562

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311071
  • Rabbit Monoclonal antibody against NHERF1 (SLC9A3R1)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401364) , 20ug
100ul 325 Next Day
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WB(1)
IHC(1)
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Also for SLC9A3R1 (NM_004252)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human NHERF1 was used as an immunogen.
Clone NameEPR5562 IsotypeTissue culture supernatant
Species ReactivityHuman, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
BufferDoes not react with Mouse. Is unsuitable for Flow Cyt,ICC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 (SLC9A3R1)
Alternative NameEBP50; NHERF; NHERF-1; NHERF1; NPHLOP2
Database LinkNP_004243
FunctionNHERF1 is a sodium/hydrogen exchanger regulatory cofactor. It interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. NHERF1 also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. It localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in NHERF1 result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this protein is implicated in breast cancer (1).
Related Pathway

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WB Image
Western blot - EBP50 antibody [EPR5562]; All lanes : Anti-EBP50 antibody [EPR5562] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : 293T cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : C6 cell lysate.Lane 5 : PC12 cell lysate.Lane 6 : MCF7 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 39 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - EBP50 antibody [EPR5562]; Immunohistochemical analysis of EBP50 in paraffin-embedded Human kidney tissue using TA311071 at 1/100 dilution.

 

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