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Home Antibody All anti-SLC9A3R1 antibodies

Anti-SLC9A3R1 Antibody EPR5562

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311071
  • Rabbit Monoclonal antibody against NHERF1 (SLC9A3R1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401364) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(1)
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Also for SLC9A3R1 (NM_004252)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human NHERF1 was used as an immunogen.
Clone NameEPR5562 IsotypeTissue culture supernatant
Species ReactivityHuman, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
BufferDoes not react with Mouse. Is unsuitable for Flow Cyt,ICC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 (SLC9A3R1)
Alternative NameEBP50; NHERF; NHERF-1; NHERF1; NPHLOP2
Database LinkNP_004243
FunctionNHERF1 is a sodium/hydrogen exchanger regulatory cofactor. It interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. NHERF1 also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. It localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in NHERF1 result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this protein is implicated in breast cancer (1).
Related Pathway

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WB Image
Western blot - EBP50 antibody [EPR5562]; All lanes : Anti-EBP50 antibody [EPR5562] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : 293T cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : C6 cell lysate.Lane 5 : PC12 cell lysate.Lane 6 : MCF7 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 39 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - EBP50 antibody [EPR5562]; Immunohistochemical analysis of EBP50 in paraffin-embedded Human kidney tissue using TA311071 at 1/100 dilution.

 

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