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Anti-SLC9A3R1 Antibody EPR5562
Also for SLC9A3R1 (NM_004252)
|A synthetic peptide corresponding to residues in human NHERF1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
|Does not react with Mouse. Is unsuitable for Flow Cyt,ICC or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt,ICC or IP.
|Homo sapiens solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 (SLC9A3R1)|
|EBP50; NHERF; NHERF-1; NHERF1; NPHLOP2|
|NHERF1 is a sodium/hydrogen exchanger regulatory cofactor. It interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. NHERF1 also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. It localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in NHERF1 result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this protein is implicated in breast cancer (1).|
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Western blot - EBP50 antibody [EPR5562]; All lanes : Anti-EBP50 antibody [EPR5562] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : 293T cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : C6 cell lysate.Lane 5 : PC12 cell lysate.Lane 6 : MCF7 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 39 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - EBP50 antibody [EPR5562]; Immunohistochemical analysis of EBP50 in paraffin-embedded Human kidney tissue using TA311071 at 1/100 dilution.