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Home Antibody All anti-MDK antibodies

Anti-MDK Antibody EP1143Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310977
  • Rabbit Monoclonal antibody against Midkine (C-term) (MDK)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC423327) , 20ug
100ul $325 3-7 Days
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Also for MDK (NM_001012333)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human Midkine was used as an immunogen.
Clone NameEP1143Y IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application * Suggested DilutionsWB: 1:1000 - 2000; IP: 1:50;
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens midkine (neurite growth-promoting factor 2) (MDK), transcript variant 2
Alternative NameARAP; MK; NEGF2
Database LinkNP_001012333
FunctionMidkine (MK) is a 13 kDa heparin-binding polypeptide which enhances neurite outgrowth, neuronal cell survival and plasminogen activator activity. MK is structurally divided into two domains, and most of the biological activities are located on the C-terminal domain. Both domains consist of three antiparallel beta-strands, but the C-terminal domain has a long flexible hairpin loop where a heparin-binding consensus sequence is located (1). MK is a member of a highly conserved, developmentally regulated human gene family. The gene product exhibits neurite outgrowth-promoting activity and may play a role in nervous system development and/or maintenance. Expression of MK is predominant only for a short period from approximately one-half to two-thirds of the way through gestation; before and after that, it is barely detectable (2).
Related Pathway

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