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Home Antibody All anti-ITGA2 antibodies

Anti-ITGA2 Antibody EPR5789

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310954
  • Rabbit Monoclonal antibody against CD49b/Integrin alpha-2 (ITGA2)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400802) , 20ug
100ul $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human CD49b/Integrin alpha-2 was used as an immunogen.
Clone NameEPR5789 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2), transcript variant 1
Alternative NameBR; CD49B; GPIa; HPA-5; VLA-2; VLAA2
Database LinkNP_002194
FunctionCD49b/Integrin alpha-2 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain (1). Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix (2).
Related Pathway
Focal Adhesion
Hematopoietic cell lineage
Hemostasis

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WB Image
Western blot - Integrin alpha 2 antibody [EPR5789]; All lanes : Anti-Integrin alpha 2 antibody [EPR5789] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : T47-D cell lysate .Lane 3 : A431 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 129 kDa.

 

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