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Home Antibody All anti-ULK3 antibodies

Anti-ULK3 Antibody EPR4888

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310926
  • Rabbit Monoclonal antibody against ULK3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC420458) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for ULK3 (NM_001099436)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human ULK3 was used as an immunogen.
Clone NameEPR4888 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; ICC: 1:25 - 1:50; FC: 1:10 - 1:100; IHC-P: 1:50 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens unc-51 like kinase 3 (ULK3), transcript variant 1
Alternative NameDKFZp434C131; FLJ90566
Database LinkNP_001092906
Entrez Gene 25989 Human
FunctionULK3 is a serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. It may exert this function by promoting GLI1 nuclear localization. ULK3 phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently (1).
Related PathwayProtein KinaseDruggable Genome Regulation of autophagymTOR signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-ULK3 antibody [EPR4888]; All lanes : Anti-ULK3 antibody [EPR4888] at 1/1000 dilution.Lane 1 : Human heart lysate.Lane 2 : Human testis lysate.Lane 3 : Human fetal kidney lysate.Lane 4 : LnCaP cell lysate.Lane 5 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 53 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ULK3 antibody [EPR4888]; TA310926, at a 1/50 dilution, staining ULK3 in paraffin embedded Human bladder carcinoma tissue by Immunohistochemistry.

 

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